ShaoBo Zhang, Christopher Amourda, Timothy Saunders. Selective Filopodia Adhesion Ensures Robust Cell Matching in the Drosophila Heart. bioRxiv 222018 doi: https://doi.org/10.1101/222018
 Heidi Connahs, Sham Tlili, Jelle van Creij, Tricia Y. J. Loo, Tirtha Banerjee, Timothy E. Saunders, Antonia Monteiro. Disrupting different Distal-less exons leads to ectopic and missing eyespots accurately modeled by reaction-diffusion mechanisms. bioRxiv 183491; doi: https://doi.org/10.1101/183491
 Katerina Karkali, George Panayotou, Timothy E Saunders, Enrique Martin-Blanco. The architectural balance of the Ventral Nerve Cord depends on the level of JNK signaling activity. bioRxiv 092486; doi: https://doi.org/10.1101/092486
 Kaur P, Saunders TE, and Tolwinski NS. Coupling optogenetics and light-sheet microscopy, a method to study Wnt signaling during embryogenesis. Sci Rep 2017; 7(1):16636. [PMID: 29192250]
 Rupprecht J, Ong KH, Yin J, Huang A, Dinh H, Singh AP, Zhang S, Yu W, and Saunders TE. Geometric constraints alter cell arrangements within curved epithelial tissues. Mol. Biol. Cell 2017;. [PMID: 28978739]
 Huang A, Amourda C, Zhang S, Tolwinski NS, and Saunders TE. Decoding temporal interpretation of the morphogen Bicoid in the early Drosophila embryo. Elife 2017; 6. [PMID: 28691901]
 Saunders TE. Imag(in)ing growth and form. Mech. Dev. 2017;. [PMID: 28351699]
 Sun Z, Amourda C, Shagirov M, Hara Y, Saunders TE, and Toyama Y. Basolateral protrusion and apical contraction cooperatively drive Drosophila germ-band extension. Nat. Cell Biol. 2017;. [PMID: 28346438]
 A. P. Singh, R. Galland, M. L. Finch-Edmondson, G. Grenci, J.-B. Sibarita, V. Studer, V. Viasnoff, and T. E. Saunders. 3D Protein Dynamics in the Cell Nucleus. Biophysical Journal 112, 133-142 (2017). Link: http://www.cell.com/biophysj/abstract/S0006-3495(16)34265-5
 C. Amourda and T. E. Saunders. Gene expression boundary scaling and tissue size regulation in the Drosophila embryo. Development, Growth and Differentiation 59, 21-32 (2017). Link: http://onlinelibrary.wiley.com/doi/10.1111/dgd.12333/full
 Jan W Krieger, Anand P Singh, Nirmalya Bag, Christoph S Garbe, Timothy E Saunders, Jörg Langowski & Thorsten Wohland. Imaging fluorescence (cross-) correlation spectroscopy in live cells and organisms. Nature Protocols 10, 1948–1974 (2015) doi:10.1038/nprot.2015.100 (November 2015).
 Matteo Rauzi, Uros Krzic, Timothy E. Saunders, Matej Krajnc, Primož Ziherl, Lars Hufnagel & Maria Leptin. Embryo-scale tissue mechanics during Drosophila gastrulation movements. Nature Communications 6, Article number: 8677 doi:10.1038/ncomms9677 (October 2015).
 David M Richards, Timothy E Saunders. 2015. Spatiotemporal Analysis of Different Mechanisms for Interpreting Morphogen Gradients. Biophysical Journal. DOI: http://dx.doi.org/10.1016/j.bpj.2015.03.015.
 Saunders TE. 2015. Aggregation-fragmentation model of robust concentration gradient formation. Physical Review E. 91. 022704. doi: 10.1103/PhysRevE.91.022704.
 J. Erceg, T. E. Saunders, C. Giradout, Damien P. Devos, L. Hufnagel and E. E. Furlong. Subtle changes in motif positioning cause tissue-specific effects on robustness of enhancer activity. PLoS Genetics, e1004060 (January 2014).
 U. Krzic, S. Gunther, T. E. Saunders, S. Streichan and L. Hufnagel. Multiview light-sheet microscope for rapid in toto imaging. Nature Methods 9, 730-733 (June 2012).
 T. E. Saunders*, K. Z. Pan*, A. Angel, Y. Guan, J. V. Shah, M. Howard and F. Chang. Noise reduction in the intracellular Pom1p gradient by a dynamic clustering mechanism. Developmental Cell 22 , 558-572 (February 2012).
 U. Krzic, T. E. Saunders, S. Streichan and L. Hufnagel. Using Scientic CMOS Technology for Fast 3D Imaging with Selective-Plane Illumination. Microscopy and analysis 26 (January 2012).
 F. He*, T. E. Saunders*, Y. Wen*, D. Cheung, R. J. Jiao, P. R. ten Wolde, M. Howard and J. Ma: Shaping a morphogen gradient for positional precision. Biophysical Journal 99, 697-707 (August 2010).
 A. Andreanov, J. T. Chalker, T. E. Saunders and D. Sherrington: Spin glass transition in geometrically frustrated antiferromagnets with weak disorder. Physical Review B 81, 014406 (January 2010). This paper was an Editor's Suggestion of the month.
 T. E. Saunders and M. Howard: When it pays to rush: interpreting morphogen gradients prior to steady-state. Physical Biology 6 , 046020 (November 2009). Physical Biology chose this paper as one of its "Highlights of the Year 2009".
 T. E. Saunders and M. Howard: Morphogen Profiles Can Be Optimised to Buffer Against Noise. Physical Review E 80, 041902 (October 2009). Recommended by Faculty of 1000.
 T. Pickles, T. E. Saunders and J. T. Chalker: Critical phenomena in a highly constrained classical spin system: Neel ordering from the Coulomb phase. Europhysics Letters 84 , 36002 (October 2008).
 T. E. Saunders and J. T Chalker: Structural phase transitions in geometrically frustrated antiferromagnets. Physical Review B 77 , 214438 (June 2008).
 T. E. Saunders and J. T. Chalker: Spin Freezing in Geometrically Frustrated Antiferromagnets with Weak Disorder. Physical Review Letters 98 , 157201 (April 2007).
* denotes equal author contribution
A. Singh et al.: Doing is understanding: science fun in India. Science in Schools 34, November 2015.
In India, as in many countries, the main focus in science classrooms is on exams rather than musing on the fascinating concepts and understanding of the world that science offers. This can mean that students lose interest in studying science – a problem that is further hampered where there is a lack of facilities, expertise or mentors. We started the ‘Science is fun’ outreach programme to address these problems. The 15-person team, led by undergraduate and research scientists, conducted four workshops with underprivileged children in Indian primary and secondary schools during December 2014 and January 2015. Read the article >>
T. E. Saunders: The physics of crowds. Science in Schools 21, December 2011.
The physics of crowds is an active area of research in many fields, from public safety to protein interactions. Crowds occur in many places: people entering stadia, traffic jams, animal migrations (e.g. wildebeest or salmon), and molecular crowding inside cells. Timothy Saunders explains why this is interesting to scientists and how to study the phenomenon in class. Read the article >>
"...Timothy Saunders, a post-doctoral researcher in biophysics and developmental biology at the prestigious European Molecular Biology Lab (EMBL Heidelberg) said: "Understanding how embryos compensate for variability, for example, temperature changes, is a major challenge in developmental biology. A multitude of mechanisms, from gene regulatory networks to mechanical feedback, ensure robust development."
"...These new Singapore NRF Fellows will begin their research shortly in their respective host institutions in Singapore." Read the article >>
The Saunders Lab is always looking for qualified individuals to join our group. Contact Timothy Saunders at dbsste "at" nus.edu.sg
Mechanobiology Institute, Singapore (MBI)
National University of Singapore T-Lab,
#10-01 5A Engineering Drive 1
Telephone: +65 66011552
Email: dbsste "at" nus.edu.sg